Events

• The São Tomé settlement is founded.
• April 9 - Edward V becomes King of England.
• April 30 - Orbital calculations suggest that on this day Pluto moved inside Neptune's orbit, making Neptune the furthest planet from the Sun until July 23, 1503.
• April - King Edward V of England and his younger brother Richard, Duke of York reside in the Tower of London. Later this year rumors of their murders start circulating. By December the rumors have reached France. This is the beginning of the mystery concerning the fates of the two Princes in the Tower.
• May 14 - Coronation of Charles VIII of France ("Charles l'Affable").
• June 13 - Execution of William Hastings, 1st Baron Hastings, the first recorded execution at the Tower of London.
• June 25 - Before his coronation King Edward V of England is deposed by his uncle, Richard, Duke of Gloucester, who becomes King as Richard III of England.
• July 6 - Richard III crowned king of England.
• August 9 - Opening of the Sistine Chapel.
• October - A rebellion by the Duke of Buckingham is crushed by Richard III.
• Isaac Abravanel flees Portugal after being implicated in a plot against the king.

Births

• January 12 - Henry III of Nassau-Breda, Baron of Breda (died 1538)
• February 14 - Zahir al-Din Mohammed Babur Shah, founder of the Moghul dynasty (died 1530)
• March 6 - Francesco Guicciardini, Italian historian (died 1540)
• April 6 - Rafael, Italian painter and architect (died 1520)
• October 16 - Gasparo Contarini, Italian diplomat and cardinal (died 1542)
• November 10 - Martin Luther, German monk and protestant reformer (died 1546)
• December 3 - Nicolaus Von Amsdorf, German protestant reformer (died 1565)
• Cacamatzin, Aztec ruler (died 1520)
• Jacquet of Mantua, French composer (died 1559)
• Chen Chun, Chinese painter (died 1544)