Parasite Eve is the name of a Japanese novel by Hideaki Sena, first published in Kadokawa Horror Bunko, which has been adapted into a 1997 film and a 1998 video game for the Sony PlayStation by Squaresoft. A sequel to the game was released in 1999, also for the PlayStation.

The story of the novel and movie revolve around a geneticist whose research in mitochondria causes him to take extreme measures to revive his wife, and eventually leads to the creation of a new threat to all mankind. The scientific basis for the story is the endosymbiotic theory: mitochondria were originally free-living bacteria, which coevolved with host cells to become mutually interdependent. The fictional premise is that mitochondria are able to rebel and to develop unusual capabilities. In addition, scientists traced mitochondrial DNA, which is inherited matrilineally, to a single woman in Africa. They dubbed her, "Mitochondrial Eve." This report appeared in "Nature" in 1987.

In reality, roughly 99% of the original mitochondrial genome has been lost or transferred to the host cell nucleus, so their evolutionary potential is actually very limited. It is far more likely that full-fledged symbiotic bacteria would rebel (as occurs, less spectacularly, in pathogenic E. coli strains).

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#RPG Series in order I've played (2): Parasite Eve, Chrono Trigger, Evolution (DC), Mobile Suit Gundam Cross Dimention 0083, Xenosaga...
NekoArc (Arcueid Brunestud) Tue, 17 Nov 2009 19:10:26 -0000
#RPG Series in order I've played (2): Parasite Eve, Chrono Trigger, Evolution (DC), Mobile Suit Gundam Cross Dimention 0083, Xenosaga...

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