PLC may stand for:

In technology:

• Packet Loss Concealment, a technique to mask the effects of missing packets in VoIP communications
• Power line communication, including broadband PLC modes
• Programmable logic controller, a small special-purpose computer used to automate machines

In business:

• Product life cycle, the succession of stages a product goes through
• Public limited company, in UK or Ireland, a type of limited company whose shares may be sold to the public